Confocal Raman AFM Imaging of Pharmaceutical Samples

AFM-Raman Characterization of Pharmaceutical Tablets

It is also useful in revealing the presence of impurities and structural disorder in materials, studying stress distributions, and temperature effects. Integration of Raman spectroscopy with Atomic Force Microscopy (AFM) opens a wide range of new capabilities in imaging and characterizing pharmaceutical products. For example, AFM topographic imaging provides information on the size of grains, t...

Confocal Raman Microscopy in Pharmaceutical Development

Imaging of single endothelial cells – Raman spectroscopy , AFM and SNOM

Hydrocarbons in phlogopite from Kasenyi kamafugitic rocks (SW Uganda): cross-correlated AFM, confocal microscopy and Raman imaging

This study presents a cross-correlated surface and near surface investigation of two phlogopite polytypes from Kasenyi kamafugitic rocks (SW Uganda) by means of advanced Atomic Force Microscopy (AFM), confocal microscopy and Raman micro-spectroscopy. AFM revealed comparable nanomorphology and electrostatic surface potential for the two mica polytypes. A widespread presence of nano-protrusions l...

Confocal Raman Spectroscopy and AFM for Evaluation of Sidewalls in Type II Superlattice FPAs

We propose to utilize confocal Raman spectroscopy combined with high resolution atomic force microscopy (AFM) for nondestructive characterisation of the sidewalls of etched and passivated small pixel (24μm×24μm) focal plane arrays (FPA) fabricated using LW/LWIR InAs/GaSb type-II strained layer superlattice (T2SL) detector material. Special high aspect ratio Si and GaAs AFM probes, with tip leng...